14 Things You Should Know About Ozempic

Recently, Ozempic has emerged as a groundbreaking weight loss solution. When every celebrity and social media influencer is raving about it, you can’t help but be curious! Originally developed for Type 2 diabetes, Ozempic has gained attention for helping with weight loss. But does Ozempic live up to the hype? 

The United States has been dealing with rising obesity rates. According to recent stats from the CDC, about 42.4% of American adults were considered obese in 2017-2018. In this scenario, Ozempic seems like a ray of hope for tackling the obesity pandemic. But at what cost and side effects?

Data shows that participants lost an average of 10% or more of their body weight. Specifically, 37-65% of those receiving 0.1 mg or more of semaglutide achieved this weight loss, compared to only 10% of participants on a placebo. However, if you want to give it a try, it is crucial to gather as much information about the drug. Here are 14 things you need to know before using Ozempic (and of course, always consult your doctor).

1. What is Ozempic?

Ozempic, known by its generic name semaglutide, is a prescription medication that belongs to a class of drugs called GLP-1 receptor agonists. It is used mainly for two purposes. When combined with diet and exercise, it helps control blood sugar in adults with type 2 diabetes. Though it is approved for diabetes, one of its side effects—weight loss—has become beneficial for many. 

Because of its success in helping with weight loss, doctors often prescribe Ozempic off-label for people with obesity, especially if they have other health issues like prediabetes or high blood pressure.

This makes sense, as another medication called Wegovy, which has the same active ingredient, is FDA-approved specifically for weight loss. The main difference is that Ozempic is used in slightly lower doses than Wegovy.

2. Ozempic Mimics GLP-1 Hormone

Ozempic works by mimicking a hormone called GLP-1 (glucagon-like peptide-1), which helps control blood sugar levels. After eating, GLP-1 triggers the pancreas to release insulin, which lowers blood sugar by helping it enter cells. GLP-1 also stops the release of glucagon, which raises blood sugar by prompting the liver to produce glucose. 

It also slows down how quickly the stomach empties, making you feel full longer and eat less, aiding in weight loss and better blood sugar control.

3. Who Should Not Use Ozempic?

Ozempic is not recommended for certain people due to potential health risks. People with the following conditions should avoid using Ozempic: Type 1 diabetes, as it is specifically for type 2 diabetes and not effective for type 1. Anyone with a personal or family history of medullary thyroid carcinoma (MTC) should not use Ozempic due to the increased risk of thyroid tumors. 

Those with Multiple Endocrine Neoplasia Syndrome Type 2 (MEN 2) should also avoid it, as it can increase the risk of thyroid cancer. Individuals with severe gastrointestinal disease, such as gastroparesis, should not take Ozempic because it may slow gastric emptying and worsen these conditions. Anyone who has had severe allergic reactions to semaglutide or any of its ingredients should refrain from using Ozempic. Also, you shouldn’t take the drug if you are less than 18 years old. 

4. Ozempic Administration

Ozempic is a once-weekly subcutaneous injection that patients can self-administer using a pre-filled, reusable pen. It’s recommended to have your healthcare provider demonstrate the proper technique for using Ozempic. Once trained, you can comfortably administer the injections at home without assistance. 

Ozempic should be taken on the same day each week, any time of the day, with or without food.

5. Dosage Information

The starting dose of Ozempic for adults is 0.25 mg injected under the skin once a week. This initial dose helps patients get used to the medication and lowers the risk of stomach-related side effects. Keep in mind the 0.25 mg dose doesn’t control blood sugar and shouldn’t be used as the regular dose.

After four weeks, the dose should be increased to 0.5 mg once a week. If more blood sugar control is needed, the dose can be increased to a maximum of 1 mg once a week, but only after at least four weeks on the 0.5 mg dose. Dosage adjustments depend on how each patient responds to and tolerates the medication.

6. Potential Side Effects

Ozempic, like any medication, may cause side effects. Common ones include nausea, vomiting, diarrhea, abdominal pain, and constipation, which usually improve as your body adjusts. If these issues are severe or don’t go away, consult a healthcare provider.

Low blood sugar (hypoglycemia) is another possible side effect, especially when taken with other diabetes medications like insulin. Symptoms include dizziness, sweating, confusion, and shaking.

Rarely, Ozempic can cause serious side effects like pancreatitis, Diabetic retinopathy, kidney issues, and severe allergic reactions. There’s also a potential risk of thyroid tumors, including medullary thyroid carcinoma, observed in animal studies.

7. Ozempic for Weight Loss

How much weight can you lose with Ozempic? While results may vary, clinical trials with 175 patients showed an average weight loss of 15 pounds after three months using Ozempic doses of 1.7 to 2.4 mg. 

This effect is particularly beneficial for those with type 2 diabetes, as weight management plays a crucial role in improving insulin sensitivity and overall metabolic health. However, it is essential to use Ozempic as part of a comprehensive weight management plan, including a balanced diet and regular physical activity. 

Patients should consult their healthcare provider to discuss the potential benefits and risks of using Ozempic for weight loss, especially if weight reduction is a primary goal.

8. Ozempic Interacts with Other Medications

Like any medication, Ozempic can also counteract other drugs in a way that may alter its efficacy or enhance side effects. For instance, using Ozempic with other diabetes medications can raise the risk of low blood sugar. Medicines like insulin or sulfonylureas should be used carefully with Ozempic.

Some drugs, such as certain antibiotics or stomach acid medications, can affect how well Ozempic is absorbed. In any case, remember to disclose to your healthcare provider any medication that you happen to be taking in this respect, whether it is a prescription drug, a medicine you can buy over the counter, or an herbal remedy.

9. Ozempic Storage

Ozempic should be stored in the refrigerator at a temperature between 36°F and 46°F (2°C and eight °C). However, if needed, the pen can be kept at room temperature, not exceeding for up to 56 days after first use.

It is important to protect the medication from light and to keep it in its original packaging when not in use. Additionally, do not freeze Ozempic. If the pen has been frozen or exposed to temperatures below 30°C, it should not be used. 

10. Cost and Insurance Coverage

The cost of Ozempic may be cheaper or more expensive depending on the insurance type and the pharmacy you buy from. Moreover, if you are taking the drug for off-label use, health insurance plans might not pay for Ozempic. 

However, if the costs are an issue, it’s advisable to consult your insurance company or seek help from the patient support program for patients who may offer a discount on the prices.

11. What to Do if You Miss a Dose?

If you miss a dose of Ozempic, it is important to take action as soon as possible, but there are specific guidelines to follow. If you remember, within five days of missing your scheduled dose, take the missed dose immediately. 

Then, continue with your next dose at your regular scheduled time. If it has been more than five days, skip the missed dose and take your next dose at your regular scheduled time. It is crucial not to take two doses at the same time to make up for the missed dose, as this can increase the risk of side effects.

12. Ozempic During Pregnancy and Breastfeeding

Ozempic has not been categorized as safe to use in pregnant or breastfeeding women. Pregnant women, women who are planning to become pregnant, or ones who are breastfeeding should consult about the possible risks and benefits relating to the administration of Ozempic with the doctor.

13. Ozempic and Alcohol

When taking Ozempic, it’s important to be cautious with alcohol. Alcohol can cause unpredictable changes in blood sugar levels, either raising or lowering them depending on the type and amount consumed.

For people with type 2 diabetes on Ozempic, these fluctuations can be tough to handle. Mixing alcohol with Ozempic might increase the risk of hypoglycemia (low blood sugar), especially if you’re also on other medications that lower blood sugar.

Alcohol can also worsen side effects like nausea and stomach discomfort. So, it’s crucial to keep an eye on your alcohol intake. It’s a good idea to talk to your healthcare provider about drinking alcohol while on Ozempic and how it might affect your treatment. 

14. Method of Disposing Of Ozempic Pens

If you use Ozempic pens, you must know the method of disposal. Do not discard empty pens in household waste bins. Instead, utilize a sharps disposal container or follow local regulations for safe disposal. Consult your doctor or pharmacist for detailed instructions on the correct disposal procedure.

27 Ways Real People Were Able to Lose Weight Sustainably without Extreme Dieting

Finding it challenging to lose those stubborn extra pounds, and growing more disheartened by the digits on your scale? The plethora of diets, exercise routines, and conflicting guidance can, without a doubt, feel quite bewildering. In the midst of numerous choices and contradictory information, you might naturally ponder: Where should you even commence?

27 Ways Real People Were Able to Lose Weight Sustainably without Extreme Dieting

17 Things That Happen When Someone Stops Drinking

Have you ever wondered what changes you might see in yourself once you put down the glass for good? Deciding to quit drinking, even if you don’t drink “that much,” can be life-changing. 

Studies show that alcohol consumption has been linked to over 200 diseases and around 178000 deaths in the US each year. You’re taking a decisive step towards improving your health and overall well-being by quitting drinking.

17 Things That Happen When Someone Stops Drinking